Clinical assessment incorporating a personal genome
نویسندگان
چکیده
Center for Inherited Cardiovascular Disease, Division of Cardiovascular Medicine (E A Ashley MRCP, M T Wheeler MD, F E Dewey MD, J W Knowles MD, A Pavlovic BS), Department of Medicine (Prof R B Altman MD), Department of Bioengineering (S R Quake PhD, D Pushkarev, N F Neff PhD, Prof R B Altman), Division of Medical Genetics (Prof L Hudgins MD), Department of Pediatrics (A J Butte MD, R Chen PhD, J T Dudley, A A Morgan MS), Howard Hughes Medical Institute (S R Quake, D Pushkarev, N F Neff ), and Department of Genetics (T E Klein PhD, K E Ormond MSc, C F Thorn PhD, M Woon BSE, L Gong PhD, L M Hodges PhD, D S Berlin PhD, K Sangkuhl PhD, J M Hebert MA, H Sagreiya, R Whaley BS, Prof R B Altman), Stanford University School of Medicine, Stanford, CA, USA; Center for Law and Biosciences, Stanford University School of Law, Stanford, CA, USA (Prof H T Greely JD); Division of Clinical and Biochemical Genetics, Massachusetts General Hospital, Boston, MA, USA (J V Thakuria MD); and Department of Genetics, Harvard University, Boston, MA, USA (G M Church PhD, M Chou PhD, J V Thakuria, A M Rosenbaum PhD, A W Zaranek PhD)
منابع مشابه
Clinical assessment incorporating a personal genome.
BACKGROUND The cost of genomic information has fallen steeply, but the clinical translation of genetic risk estimates remains unclear. We aimed to undertake an integrated analysis of a complete human genome in a clinical context. METHODS We assessed a patient with a family history of vascular disease and early sudden death. Clinical assessment included analysis of this patient's full genome s...
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تاریخ انتشار 2010